Subependymal heterotopia: a distinct neuronal migration disorder associated with epilepsy.

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Subependymal heterotopia: a distinct neuronal migration disorder associated with epilepsy.

Subependymal heterotopia has recently been recognised as a cause of epilepsy, but the clinical and investigational features have not been fully described. The clinical, psychometric, imaging, and electroencephalographic features of 13 adult patients with subependymal heterotopia and epilepsy have been reviewed. Age at seizure onset ranged from 18 months to 20 years (median 13 years). There were...

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A case report of surgically treated drug resistant epilepsy associated with subependymal nodular heterotopia

Subependymal nodular heterotopia (SNH) is a cortical development malformation that is commonly associated with medically resistant epilepsy. Cases of SNH are challenging to treat surgically because there are typically multiple nodules, which may be involved in epileptogenesis. Moreover, dual pathology may exist in these patients. Here, we present a case with unilateral subependymal heterotopic ...

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Neuronal Migration Disorder; A Case Report of Subcortical Band Heterotopia Associated with Corpus Callosum Agenesis

Subcortical band heterotopia (SBH) or 'double cortex' is a congenital brain abnormality that results from aberrant migration of neurons during development of the cortex. MRI shows a continuous band of heterotopic gray matter located between the cortex and ventricular walls, separated from them by a thin layer of white matter. The condition is quite rare, found predominantly in females, and is o...

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Antenatal diagnosis of subependymal heterotopia.

Subependymal heterotopia consist of gray matter nodules along the lateral ventricular walls and are associated with epilepsy and other cerebral malformations. Some cases have an X-linked inheritance, and early antenatal diagnosis of affected fetuses is important for appropriate management. We present a case of heterotopia diagnosed by sonography and MR imaging at 23 weeks' gestation and discuss...

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Reading impairment in the neuronal migration disorder of periventricular nodular heterotopia.

OBJECTIVE To define the behavioral profile of periventricular nodular heterotopia (PNH), a malformation of cortical development that is associated with seizures but reportedly normal intelligence, and to correlate the results with anatomic and clinical features of this disorder. METHODS Ten consecutive subjects with PNH, all with epilepsy and at least two periventricular nodules, were studied...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1994

ISSN: 0022-3050

DOI: 10.1136/jnnp.57.10.1195